The hotel of record for Garden Bloggers Buffa10 was Embassy Suites.

There are also two restaurants in the building and dozens on the surrounding blocks -- the Avant Espresso Bar has Starbucks coffee & pre-made salads, sandwiches & pastries.
The hotel is located in the heart of the Garden Walk area, as a matter of fact, it is across the street from one of the Garden Walk Headquarters and some rooms look over an area of concentrated Garden Walk gardens. It's also a short walk to the Erie Basin Marina University Trial Gardens, growing annuals and perennials that may come to market in 2-4 years. If you'll be driving in, here is a link for directions.
Other area hotels
Adam's Mark Buffalo Niagara 120 Church Street · Buffalo · NY · 14202 · (716) 845-5100 · Website
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Cost: $$ - Moderate
601 Main Street · Buffalo · NY · 14203 · (716) 854-5500 · Website
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Cost: $$ - Moderate
125 High Street · Buffalo · NY · 14203 · (716) 845-0112 · Website
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Cost: $$ - Moderate
220 Delaware Avenue · Buffalo · NY · 14202 · (716) 855-2223 · Website
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Cost: $$ - Moderate
620 Delaware Ave. · Buffalo · NY · 14202 · (716) 886-2121 · Website
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Cost: $$ - Moderate
Two Fountain Plaza · Buffalo · NY · 14202 · (716) 856-1234 · Website
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Cost: $$ - Moderate
Best Western Inn on the Avenue
510 Delaware Avenue · Buffalo · NY · 14202 · (716) 886-8333 · Website
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Cost: $$ - Moderate
Hostelling International - Buffalo Niagara
667 Main Street · Buffalo · NY · 14203 · (716) 852-5222 · Website
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Mansion on Delaware Avenue
414 Delaware Avenue · Buffalo · NY · 14202 · (716) 886-3300 · Website
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Cost: $$$ - Luxury
361 Porter Avenue · Buffalo · NY · 14201 · (716) 885-9341
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Cost: $$ - Moderate